Tag: M.W:200-300

It is a common heterocyclic compound, the iron-catalyst compound, Ferrocenemethanol, cas is 1273-86-5 its synthesis route is as follows.

General procedure: Method A (Table 2, entries 1,4). Into a glass 50-mL flask equipped with a stirrer, a reflux condenser,a thermometer, a bubbler for propyne supply, and a gasoutlet, alcohol 1a,b (5.0 mmol), KPO0.5O2P (0.16 g, 2.5 mmol),and DMSO (30 mL) were placed. Propyne was passed on stirring for2 h through the reaction mixture heated up to 80 C. After coolingto room temperature the reaction mixture was diluted with anaqueous 1% solution of NH4Cl (50 mL) and extracted with ether(530 mL), the extracts were washed from DMSO by water(230 mL), dried over Na2SO4. Column chromatography (basicAl2O3, eluent hexane/diethyl ether with gradient from 1:0 to 3:1) ofthe crude residue after removal of the solvent gave the pure adducts2c,d and unreacted alcohols 1a,b.

1273-86-5, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,1273-86-5 ,Ferrocenemethanol, other downstream synthetic routes, hurry up and to see

Reference£º
Article; Trofimov, Boris A.; Oparina, Ludmila A.; Tarasova, Olga A.; Artem’ev, Alexander V.; Kobychev, Vladimir B.; Gatilov, Yuriy V.; Albanov, Alexander I.; Gusarova, Nina K.; Tetrahedron; vol. 70; 35; (2014); p. 5954 – 5960;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

1287-16-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Ferrocenylacetic acid, cas is 1287-16-7,the iron-catalyst compound, it is a common compound, a new synthetic route is introduced below.

In a 50mL three neck round bottom flask, ferroceneacetic acid (0.0600g, 0.25mmol), oxalyl chloride (21.8muL, 0.25mmol), pyridine (20.1muL, 0.25mmol) and 4-(1H-pyrrol-1yl)phenol (0.0398g, 0.25mmol) were reacted in 10mL of dichloromethane (DCM) under nitrogen atmosphere at room temperature. The reaction was carried out for 12h to get 4(1H-pyrrol-1-yl)phenyl ferroceneacetylate. After that period three consecutive washing with 0.01M HCl were carried out. The organic phase was then dried over sodium sulfate. The product was separated by column chromatography using silica gel and DCM as mobile phase. Fc-CH2CO2-Ph-4-Py was isolated in 62% yield.

The chemical industry reduces the impact on the environment during synthesis,1287-16-7,Ferrocenylacetic acid,I believe this compound will play a more active role in future production and life.

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Article; Perez, Wanda I.; Soto, Yarelys; Ortiz, Carmen; Matta, Jaime; Melendez, Enrique; Bioorganic and Medicinal Chemistry; vol. 23; 3; (2015); p. 471 – 479;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

1271-51-8, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Vinylferrocene, cas is 1271-51-8,the iron-catalyst compound, it is a common compound, a new synthetic route is introduced below.

General procedure: General procedure: In a J-Young NMR tube substrate(0.10 mmol), catalyst precursor 15 (23.5 mg, 0.02 mmol) andB(C6F5)3 (2.6 mg, 0.005 mmol) were dissolved in C6D6 (0.7 mL).After 30 min the atmosphere was removed, dihydrogen (2 bar)applied and the reaction monitored by 1H NMR spectroscopy.Conversion was determined from the 1H NMR spectra. (see theSupporting Information for control experiments and spectroscopicdata of hydrogenation products 17a-l).

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Vinylferrocene, 1271-51-8

Reference£º
Article; Woelke, Christian; Daniliuc, Constantin G.; Kehr, Gerald; Erker, Gerhard; Journal of Organometallic Chemistry; vol. 899; (2019);,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

It is a common heterocyclic compound, the iron-catalyst compound, Ferrocenecarboxylic acid, cas is 1271-42-7 its synthesis route is as follows.

Briefly, to a solution of Fc-COOH (5.65 mmol, 1.3 g) in dry DCM at 0 C, Et3N (6.19 mmol, 0.87 mL), HOBt (6.19 mmol, 0.84 g) and HBTU (6.19 mmol, 2.4 g) were added, reacted 1 h at 0 C, then 1 g H-Gly-OMe by treatment with Et3N in DCM (5 mL) was added.

1271-42-7, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,1271-42-7 ,Ferrocenecarboxylic acid, other downstream synthetic routes, hurry up and to see

Reference£º
Article; Zhou, Binbin; Li, Chun-Lan; Hao, Yuan-Qiang; Johnny, Muya Chabu; Liu, You-Nian; Li, Juan; Bioorganic and Medicinal Chemistry; vol. 21; 2; (2013); p. 395 – 402;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

1271-51-8, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Vinylferrocene, cas is 1271-51-8,the iron-catalyst compound, it is a common compound, a new synthetic route is introduced below.

General procedure: In a 25-mL round-bottomed flask, a mixture of aryl iodide (5 mmol), alkene (6 mmol), and base (5.6 mmol) was placed in 4 mL of DMF, then a solution of the complex 3 (0.005 mol percent) in 1 mL of DMF was added. The reaction mixture was refluxed for the time stated in Tables 3 and 4 at 140 ¡ãC. The reaction mixture was poured into water (20 mL) and extracted with ether or hexane (2¡Á30 mL). The combined organic layers were dried over anhydrous sodium sulfate. After the removal of the solvent in vacuo, the resulting crude was purified by column chromatography on silica gel (hexane/ethyl acetate) to give the corresponding cross-coupling product (the purified product was identified by means of determination of mp and by 1H and 13C NMR, the data obtained are consistent with literature).26 The entire flasks used in the each coupling reaction were meticulously cleaned with aqua regia to avoid the presence of unseen palladium catalyst.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Vinylferrocene, 1271-51-8

Reference£º
Article; Sua?rez-Meneses, Jesu?s V.; Bonilla-Reyes, Edgar; Ble?-Gonza?lez, Ever A.; Ortega-Alfaro, M. Carmen; Toscano, Rube?n Alfredo; Cordero-Vargas, Alejandro; Lo?pez-Corte?s, Jose? G.; Tetrahedron; vol. 70; 7; (2014); p. 1422 – 1430;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

1273-86-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Ferrocenemethanol, cas is 1273-86-5,the iron-catalyst compound, it is a common compound, a new synthetic route is introduced below.

Ferrocenemethanol (1.3 mmol), 4-methylaniline (1 mmol), carbon-supported ruthenium nanomaterial (20 mg),Potassium hydroxide (20 mg) was added to a 25 ml reaction tube with a magnetic stirrer.After repeated nitrogen suction three times, toluene (3 ml) was added via a syringe and then sealed and reacted at 110C for 24 hours.After the reaction is completed, the catalyst is removed by filtration, and the filtrate is extracted by adding water and ethyl acetate, and the organic phases are combined.After drying, filtration, concentration under reduced pressure, and silica gel column chromatography, N-(ferrocenyl)aniline (yield 85%) was obtained.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Ferrocenemethanol, 1273-86-5

Reference£º
Patent; Soochow University (Suzhou); Li Hongxi; Guo Bin; Lang Jianping; (16 pag.)CN107954879; (2018); A;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

1273-82-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Aminoferrocene, cas is 1273-82-1,the iron-catalyst compound, it is a common compound, a new synthetic route is introduced below.

General procedure: 1a was synthesized by modifying the reported procedure [44]. Catalytic amount of p-toluene sulfonic acid (20mg, 0.10mmol) was added to a mixture of pyrrole-2-carbaldehye (380mg, 4.0mmol) and 1-amino-2-methoxybenzene (490mg, 4.0mmol) in methanol (10mL) under stirring condition in nitrogen atmosphere. The resulting mixture was heated to reflux for 20h, and then cooled to room temperature. After removal of volatiles under reduced pressure, the residue was mixed with THF and filtered through a pad of celite. The resulting solution was concentrated to give a brown solid, which was further purified by re-dissolved in THF/ether (1:4). The solution was kept at -18C for overnight, and brown crystalline solid was collected by filtration. The solid was washed with ether and further dried under vacuum to obtain 1a. Yield 270mg (68%). m.p. 235-236C. 1H NMR (400MHz, CDCl3) delta 10.07 (s, 1H, NH), 8.30 (s, 1H, CH=N), 7.20 (dt, J=7.6, 1.6Hz, 1H, Ar-H), 7.05 (d, J=1.6Hz, 1H, Ar-H), 7.01 (d, J=7.6Hz, 1H, Ar-H), 6.98 (d, J=7.6Hz, 1H, Ar-H), 6.88 (d, J=1.2Hz, 1H, Py-H), 6.70 (dd, J=1.2, 3.6Hz, 1H, Py-H), 6.30 (d, J=3.6Hz, 1H, Py-H), 3.88 (s, 3H, CH3). 13C NMR (100MHz, CDCl3) delta 152.52, 150.71, 141.82, 130.95, 126.63, 123.32, 121.36, 120.74, 116.69, 111.42, 110.47, 55.84. MS (ESI) m/z: 200.5. Anal. Calcd for C12H12N2O: C 71.98, H 6.04, N 13.99. Found: C 71.96, H 6.30, N 13.83.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Aminoferrocene, 1273-82-1

Reference£º
Article; Zhuo, Ji-Bin; Ma, Zai-He; Lin, Cai-Xia; Xie, Li-Li; Bai, Sha; Yuan, Yao-Feng; Journal of Molecular Structure; vol. 1085; (2015); p. 13 – 20;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

1287-16-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Ferrocenylacetic acid, cas is 1287-16-7,the iron-catalyst compound, it is a common compound, a new synthetic route is introduced below.

General procedure: A mixture of ferrocene acetic acid (1 mmol), the required 3-substituted-4-amino-5-mercapto-1,2,4-triazole(1 mmol), and p-toluenesulfonic acid (0.1 mmol) in DMF(10 mL) was stirred until a homogeneous solution was obtained. The mixture was exposed to microwave irradiation for about 3 min at 350 W and then cooled and poured into crushed ice. The mixture was adjusted to pH 7 with potassium carbonate and potassium hydroxide and then kept overnight at room temperature. The crude product was filtered off, dried and recrystallized from 80% ethanol to afford the pure product (Scheme 1).

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Ferrocenylacetic acid, 1287-16-7

Reference£º
Article; Liu, Yuting; Xin, Hong; Yin, Jingyi; Yin, Dawei; Transition Metal Chemistry; vol. 43; 5; (2018); p. 381 – 385;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Name is Aminoferrocene, as a common heterocyclic compound, it belongs to iron-catalyst compound, and cas is 1273-82-1, its synthesis route is as follows.

General procedure: Aminoferrocene (1, 11.0 mg, 0.0547 mmol) was dissolved in 9 cm3 toluene. Formylphenylboronic acid (2, 8.2 mg,0.0547 mmol) was dissolved in 1 cm3 dry ethanol. Both reagent solutions were mixed in an evaporating flask. The solvents were removed under reduced pressure on a rotary vacuum evaporator (the water bath temperature strictly below 40 C) to give [(ferrocenylimino)methyl]phenylboronic acid 3 as a violet/red powder; 18.2 mg (quant.). The products were used as prepared without need of a further purification (Fig. 5).

1273-82-1, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,1273-82-1 ,Aminoferrocene, other downstream synthetic routes, hurry up and to see

Reference£º
Article; Konhefr, Martin; Lacina, Karel; Langmajerova, Monika Skrutkova; Glatz, Zden?k; Skladal, Petr; Mazal, Ctibor; Monatshefte fur Chemie; vol. 148; 11; (2017); p. 1953 – 1958;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

As a common heterocyclic compound, it belongs to iron-catalyst compound, name is Ferrocenecarboxylic acid, and cas is 1271-42-7, its synthesis route is as follows.

A solution of ferrocene carboxylic acid (2.3 g, 10 mmol) in dry dichloromethane (20 ml.) was treated with oxalyl chloride dropwise (1.8 ml_, 20 mmol) at 0 C under nitrogen with the addition of four drops of DMF. The reaction mixture was returned to r.t. and stirred for 3 hours. The solvent and the excess oxalyl chloride was removed under nitrogen, and the resulting red solid was redissolved to fresh dry dichloromethane (20 ml_). Tetrabutylammoniun bromide (12 mg, 0.03 mmol) was added followed by the addition of a NaN3 solution (1 g, 15 mmol) in water (5 ml_). The reaction mixture was stirred under nitrogen and at r.t for a further 18 h. The reaction was quenched by the addition of water (50 ml.) and the organic phase was separated, and the aqueous was further extracted with dichloromethane (2 x 20 ml_). The combined organic phase was washed with brine, dried with Na2S04 and the solvent was removed under vacuum. The desired azide was isolated by flash column chromatography eluting with dichloromethane:hexane (1 :1 ). Yield: 78%. NMR (CDCIs, ppm): 1H (500 MHz) 4.78, 4.55, 4.05; 13C (126 MHz) 176.1 , 89.0, 76.3, 78.0, 80.1.

1271-42-7, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,1271-42-7 ,Ferrocenecarboxylic acid, other downstream synthetic routes, hurry up and to see

Reference£º
Patent; NATIONAL CENTRE FOR SCIENTIFIC RESEARCH “DEMOKRITOS”; PELECANOU ZAMPARA, Maria; SAGNOU, Marina; PAPADOPOULOS, Minas; PIRMETTIS, Ioannis; MAVROIDI, Barbara; SHEGANI, Antonio; (38 pag.)WO2019/180200; (2019); A1;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion