Category: 1271-51-8

Name is Vinylferrocene, as a common heterocyclic compound, it belongs to iron-catalyst compound, and cas is 1271-51-8, its synthesis route is as follows.,1271-51-8

General procedure: In an Schlenk tube under argon one of the following central coresC1, or C2 was mixed with 5percent palladium (II) acetate, Pd(OAc)2, 10percentTris(o-tolyl)phosphine, P(o-tol)3, and vinyl ferrocene, 1-Fc, in triethylamine/THF, 15 mL/15 mL. The resulting mixture was stirred and refluxedovernight. After removing the solvent under reduced pressure,the oil obtained was washed with distillated water and extracted inCH2Cl2 three times and dried over MgSO4. The extract was concentratedto dryness and purified by column chromatography (silica gel60) using hexane/CH2Cl2 2:1 (V/V) mixtures as eluent. The correspondingcompounds were isolated after removing the solvent in a rotaryevaporator. Compound 1. 1-Fc (187 mg, 8.84 mmol), C1 (150 mg,0.253 mmol), Pd(OAc)2 (2.8 mg, 0.0126 mmol), P(o-tol)3 (7.7 mg,0.0253 mmol), triethylamine/THF, 15 mL/15 mL. Yield 49.5percent. IR wavenumber(KBr): =1713 cm?1 (eC]O), 1590 cm?1 (eC]Ce). 1HNMR (CDCl3, 400 MHz): delta=4.10 (15H, pst, C5H5), 4.27 (6H,pst?C5H4), 4.44 (6H, s, ?C5H4), 6.68 (3H, d, J=16.0 Hz, ]CH), 6.89(3H, d, J=16.0 Hz, ]CH), 7.31 (6H, d, J=8.2 Hz, Harom), 7.50 (6H, d,J=8.4 Hz, Harom). 13C NMR (100.6 MHz, CDCl3): delta=67.05, 69.25,69.66, 82.76, 124.74, 126.48, 128.53, 128.60, 128.91, 131.70, 139.04.Analysis calculated for C57H45O3Fe3N3: C, 69.3; H, 4.59; N, 4.26.Found: C, 68.61; H, 4.12; N, 4.32. MP: 199 ¡ãC – 200 ¡ãC.

With the complex challenges of chemical substances, we look forward to future research findings about Vinylferrocene

Reference£º
Article; Santos, Juan C.; Madrid-Moline, Franco; Cisternas, Carlos A.; Paul, Frederic; Escobar, Carlos A.; Jara-Ulloa, Paola; Trujillo, Alexander; Inorganica Chimica Acta; vol. 486; (2019); p. 95 – 100;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO425,mainly used in chemical industry, its synthesis route is as follows.,1271-51-8

General procedure: General procedure: In a J-Young NMR tube substrate(0.10 mmol), catalyst precursor 15 (23.5 mg, 0.02 mmol) andB(C6F5)3 (2.6 mg, 0.005 mmol) were dissolved in C6D6 (0.7 mL).After 30 min the atmosphere was removed, dihydrogen (2 bar)applied and the reaction monitored by 1H NMR spectroscopy.Conversion was determined from the 1H NMR spectra. (see theSupporting Information for control experiments and spectroscopicdata of hydrogenation products 17a-l).

With the synthetic route has been constantly updated, we look forward to future research findings about Vinylferrocene,belong iron-catalyst compound

Reference£º
Article; Woelke, Christian; Daniliuc, Constantin G.; Kehr, Gerald; Erker, Gerhard; Journal of Organometallic Chemistry; vol. 899; (2019);,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

1271-51-8, Vinylferrocene is a iron-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: 25mL reaction flask, weighing 2molpercent palladium acetate and 4molpercent ferrocenylpyrimidine multidentate ligand 6h, adding 12 water, stirring for 5min, 4 mmol of p-nitrochlorobenzene, 4.8 mmol of butyl acrylate, 6 mmol of potassium phosphate, and 0.8 mmol of tetrabutylammonium bromide were added successively. The reaction was heated to 80¡ãC until the reaction was complete (the reaction did not continue after about 6 h, and palladium black appeared in the reaction flask). After adding 25 mL of ethyl acetate and washing three times with water, the organic phases were combined, dried over anhydrous sodium sulfate, concentrated, and the residue was separated by column chromatography. PE/EA=12:1 was used as an eluent to obtain 707 mg of a yellow solid with a yield of 71percent.

1271-51-8, 1271-51-8 Vinylferrocene 16211828, airon-catalyst compound, is more and more widely used in various fields.

Reference£º
Patent; Zhengzhou University of Light Industry; Yu Shuyan; Zhang Tongyan; Wang Ruijuan; Yin Zhigang; Yang Xuzhao; Lan Hongbing; (13 pag.)CN107383112; (2017); A;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO479,mainly used in chemical industry, its synthesis route is as follows.,1271-51-8

General procedure: In an Schlenk tube under argon one of the following central coresC1, or C2 was mixed with 5percent palladium (II) acetate, Pd(OAc)2, 10percentTris(o-tolyl)phosphine, P(o-tol)3, and vinyl ferrocene, 1-Fc, in triethylamine/THF, 15 mL/15 mL. The resulting mixture was stirred and refluxedovernight. After removing the solvent under reduced pressure,the oil obtained was washed with distillated water and extracted inCH2Cl2 three times and dried over MgSO4. The extract was concentratedto dryness and purified by column chromatography (silica gel60) using hexane/CH2Cl2 2:1 (V/V) mixtures as eluent. The correspondingcompounds were isolated after removing the solvent in a rotaryevaporator.

With the synthetic route has been constantly updated, we look forward to future research findings about Vinylferrocene,belong iron-catalyst compound

Reference£º
Article; Santos, Juan C.; Madrid-Moline, Franco; Cisternas, Carlos A.; Paul, Frederic; Escobar, Carlos A.; Jara-Ulloa, Paola; Trujillo, Alexander; Inorganica Chimica Acta; vol. 486; (2019); p. 95 – 100;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Vinylferrocene, cas is 1271-51-8, it is a common heterocyclic compound, the iron-catalyst compound, its synthesis route is as follows.,1271-51-8

A mixture of vinylferrocene (1 mmol), K2CO3 (2.5or 5 mmol), tetrabutylammonium tetrafluoroborat (2.5 or 5 mmol),the given amount of appropriate bromine-substituted compoundand catalytic amount of Pd(OAC)2 in 10 ml DMF was stirred at 80 ¡ãCunder argon atmosphere overnight. After the completion of thereaction, the cooled mixture was filtered, diluted with CH2Cl2(50 ml) and washed with H2O (3 x 50 ml). The organic phase was dried over Na2SO4, filtered and the solvent was removed under thereduce pressure. The crude products were purified by columnchromatography on silica gel with hexane/EtOAC as eluent. Specificdetails for each compound are given below.

With the rapid development of chemical substances, we look forward to future research findings about Vinylferrocene

Reference£º
Article; Teimuri-Mofrad, Reza; Rahimpour, Keshvar; Ghadari, Rahim; Journal of Organometallic Chemistry; vol. 846; (2017); p. 397 – 406;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Name is Vinylferrocene, as a common heterocyclic compound, it belongs to iron-catalyst compound, and cas is 1271-51-8, its synthesis route is as follows.,1271-51-8

Under argon, into a dried reactor were added successively vinyl ferrocene (1mol, 212g), (R ) -3,3′-bis (3,5-dimethylphenyl) -1,1 ‘ – binaphthol phosphonate (0.1mol, 55g) and 1L of toluene was added dicyclohexyl phosphine (1mol, 198g), was heated to 100 deg.] C for 10 hours, then cooled cooling, water was added dropwise to the system, and then liquid separation The organic layer was dried over anhydrous magnesium sulfate, filtered, and the solvent evaporated under reduced pressure to give a yellow solid which was recrystallized from dichloromethane and methanol to give (R) -1- ferrocenyl ethyl dicyclohexylphosphino 394 g, yield 96percent, ee value of 99.4percent.

With the complex challenges of chemical substances, we look forward to future research findings about Vinylferrocene

Reference£º
Patent; Institute of Chemistry, Henan Academy of Sciences; Chen, Hui; Yang, Ruina; Yang, Zhenqiang; Sun, Minqing; Duan, Zheng; Wang, Congyang; (5 pag.)CN105859800; (2016); A;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

1271-51-8, Vinylferrocene is a iron-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: As shown as the synthetic protocol A in Scheme 2, compounds 1-11 were synthesized following literature description [16] with m-methoxyphenol, p-methoxyphenol, resorcinol, and hydroquinone as reagents. One hydroxyl group in resorcinol and hydroquinone was protected by tert-butyldimethylsilyl chloride. Then, 17 mL of dry CHCl3 solution containing excess PhtNSCl was added dropwisely to 8 mL of dry CHCl3 solution containing monoprotected hydroquinone or resorcinol and stirred for 16 h at 0 ¡ãC until phenols cannot be detected by thin layer chromatography (TLC). The mixture was diluted with CH2Cl2 and washed by saturated NaHCO3 and water. The organic phase was dried over anhydrous Na2SO4, and the solvent was removed under vacuum. The residue was purified by column chromatography with CH2Cl2 as the eluent to afford thiophthalimides as colorless solid. The following cycloaddition reactions were carried out in dry CHCl3 solution of thiophthalimides (~ 0.1 M) and styrenes (2 equiv.) or vinyl ferrocene (2 equiv.) and freshly distilled (C2H5)3N (2 equiv.) at 60 ¡ãC. The reaction was finished with thiophthalimides not detected by TLC. Then, the solvent was evaporated under vacuum pressure, and the residual solid was purified with column chromatography to afford silylated adducts. The desilylation operation was performed in dry tetrahydrofuran (THF) solution containing 0.04 M aforementioned adducts at 0 ¡ãC, to which a solution of (n-C4H9)4NF*3H2O in THF (1 equiv. for each protective group) was added. The reaction was finished with the reagent not detected by TLC, and then the mixture was diluted with ethyl acetate and washed with saturated NH4Cl and water. The organic layer was dried over anhydrous Na2SO4, and the solvent was evaporated under vacuum pressure. The residue was purified with column chromatography to afford thiaflavans.

1271-51-8, As the paragraph descriping shows that 1271-51-8 is playing an increasingly important role.

Reference£º
Article; Lai, Hai-Wang; Liu, Zai-Qun; European Journal of Medicinal Chemistry; vol. 81; (2014); p. 227 – 236;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Name is Vinylferrocene, as a common heterocyclic compound, it belongs to iron-catalyst compound, and cas is 1271-51-8, its synthesis route is as follows.,1271-51-8

Ethynylferrocene (1) (0.5 g, 2.380 mmol) was dissolved in dryethanol (35 mL) and cooled to 0 ¡ãC and subsequently treated withsolid KOH (0.340 g, 6 mmol). After 30 min of stirring at a lowtemperature solid N-iodosuccinimide (0.642 g, 2.856 mmol) wasadded to the mixture, and the stirring continued at 0 ¡ãC for additional30 min. The cold bath was then removed and the stirringcontinued at room tempreture for an additional 2 h. Aftercompletion of reaction (monitored by TLC) 100 mL of EtOAc wasadded and the mixture extracted three times with brine. Theorganic layer was separated, dried over Na2SO4, filtered, andevaporated. The productwas isolated in quantitative yield as brownSolid.Yield: 94percent (brown solid); m.p 112-115 ¡ãC (lit. 116-117 C) [47];1H NMR (500 MHz, CDCl3): delta 4.18-4.23 (m, 7H), 4.44-4.47 (m,2H) ppm; 13C NMR (75 MHz, CDCl3): delta 66.4, 69.4, 69.5, 70.6, 70.7,70.77, 70.84, 70.9, 72.5, 74.3, 92.8 ppm.

With the complex challenges of chemical substances, we look forward to future research findings about Vinylferrocene

Reference£º
Article; Yousuf, Md; Mukherjee, Debarati; Dey, Somaditya; Pal, Chiranjib; Adhikari, Susanta; European Journal of Medicinal Chemistry; vol. 124; (2016); p. 468 – 479;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Name is Vinylferrocene, as a common heterocyclic compound, it belongs to iron-catalyst compound, and cas is 1271-51-8, its synthesis route is as follows.,1271-51-8

General procedure: In a 25-mL round-bottomed flask, a mixture of aryl iodide (5 mmol), alkene (6 mmol), and base (5.6 mmol) was placed in 4 mL of DMF, then a solution of the complex 3 (0.005 mol percent) in 1 mL of DMF was added. The reaction mixture was refluxed for the time stated in Tables 3 and 4 at 140 ¡ãC. The reaction mixture was poured into water (20 mL) and extracted with ether or hexane (2¡Á30 mL). The combined organic layers were dried over anhydrous sodium sulfate. After the removal of the solvent in vacuo, the resulting crude was purified by column chromatography on silica gel (hexane/ethyl acetate) to give the corresponding cross-coupling product (the purified product was identified by means of determination of mp and by 1H and 13C NMR, the data obtained are consistent with literature).26 The entire flasks used in the each coupling reaction were meticulously cleaned with aqua regia to avoid the presence of unseen palladium catalyst.

With the complex challenges of chemical substances, we look forward to future research findings about Vinylferrocene

Reference£º
Article; Sua?rez-Meneses, Jesu?s V.; Bonilla-Reyes, Edgar; Ble?-Gonza?lez, Ever A.; Ortega-Alfaro, M. Carmen; Toscano, Rube?n Alfredo; Cordero-Vargas, Alejandro; Lo?pez-Corte?s, Jose? G.; Tetrahedron; vol. 70; 7; (2014); p. 1422 – 1430;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

1271-51-8, Vinylferrocene is a iron-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of vinylferrocene (1 mmol), K2CO3 (2.5or 5 mmol), tetrabutylammonium tetrafluoroborat (2.5 or 5 mmol),the given amount of appropriate bromine-substituted compoundand catalytic amount of Pd(OAC)2 in 10 ml DMF was stirred at 80 ¡ãCunder argon atmosphere overnight. After the completion of thereaction, the cooled mixture was filtered, diluted with CH2Cl2(50 ml) and washed with H2O (3 x 50 ml). The organic phase was dried over Na2SO4, filtered and the solvent was removed under thereduce pressure. The crude products were purified by columnchromatography on silica gel with hexane/EtOAC as eluent. Specificdetails for each compound are given below., 1271-51-8

1271-51-8 Vinylferrocene 16211828, airon-catalyst compound, is more and more widely used in various fields.

Reference£º
Article; Teimuri-Mofrad, Reza; Rahimpour, Keshvar; Ghadari, Rahim; Journal of Organometallic Chemistry; vol. 846; (2017); p. 397 – 406;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion