Reference of 1273-94-5, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1273-94-5, Name is 1,1′-Diacetylferrocene, molecular formula is C14H6FeO2. In a Article£¬once mentioned of 1273-94-5
DNA interaction, antioxidant, and in vitro antitumor activity of binuclear ruthenium(III) complexes of benzothiazole-substituted ferrocenyl thiosemicarbazones
In our search for new anticancer drugs, a series of binuclear ruthenium(III) thiosemicarbazone complexes of the type [RuCl 2(EPh3)]2L (where E = P/As; L = binucleating monobasic tridentate thiosemicarbazone ligand) have been synthesized. Structural features were determined by various physico-chemical and spectral techniques. The interactions of these complexes with CT-DNA were investigated by absorption spectral study, indicates that the binuclear ruthenium(III) complexes form adducts with DNA and has intrinsic binding constant in the range of 1.0 ¡Á 104-7.9 ¡Á 104 M-1. The free radical scavenging activity of binuclear ruthenium(III) complexes have been determined by their interaction with the stable DPPH free radical. All the complexes exhibited significant antiproliferative activity against human breast cancer line, MCF-7. This research may provide knowledge that is an excellent backdrop for the rational design of promising drugs.
DNA interaction, antioxidant, and in vitro antitumor activity of binuclear ruthenium(III) complexes of benzothiazole-substituted ferrocenyl thiosemicarbazones
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 1273-94-5, and how the biochemistry of the body works.Reference of 1273-94-5
Reference£º
Iron Catalysis in Organic Synthesis | Chemical Reviews,
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion