1273-86-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Ferrocenemethanol, cas is 1273-86-5,the iron-catalyst compound, it is a common compound, a new synthetic route is introduced below.
To a 10 ml Schlek reaction tube under a high-purity nitrogen atmosphere was added 0.20 mmol of benzoquinoline triphenylphosphine iridium hydrogen (16), lmmol of phenylacetylene, 2.3 mmol of ferrocene methanol, 0.8 mmol of sodium hydroxide and 3 ml of dioxane were charged. The reaction tube was replaced with nitrogen three times and then heated to 110 C with an oil bath under magnetic stirring. The reaction was refluxed for 36 hours. The filtrate was concentrated using a rotary evaporator and the remaining residue was purified by chromatography on oil (100 mL). The residue was purified by flash chromatography on silica gel eluting with an oil bath and the bath was cooled to room temperature. Ether as eluent, and separated by silica gel thin layer chromatography to obtain pure product 1-ferrocenyl-3-phenyl-1-propanone in a yield of 96%.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Ferrocenemethanol, 1273-86-5
Reference£º
Patent; Luoyang Normal University; Li, Xiao Dong; Li, gongmei; Xu, Chen; Hao, Xin Qi; Xiao, Zhi Qiang; (10 pag.)CN103242372; (2016); B;,
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